Dr. Zhixing Chen from the College of Future Technology, Peking University will give a presentation titled
Live-cell imaging technology is advancing into the era of dynamic super-resolution imaging, placing new demands on the optical properties of fluorescent probes. Traditional live-cell fluorescent probes face two critical technical challenges: 1. How to make fluorescent probes brighter and more photostable, 2. How to make fluorescent probes gentler to minimize photodamage. Based on the fundamental principles of photochemistry and biochemistry, we have developed a new generation of live-cell imaging probes that far surpass traditional probes in brightness, photostability, and biocompatibility. These probes enable long-term super-resolution imaging of mitochondria, insulin vesicle secretion, neural activity, cell membranes, the cytoskeleton, DNA, and more. Our representative achievements include: The PK Mito and PK Zinc dye series, widely used in mitochondrial and insulin secretion imaging. The BD series of novel fluorophores, in conjunction with self-labeling tags, offer general labeling strategies with superior optical properties compared to fluorescent proteins.
The colloquium will take place at Campus Riegberg, Biocenter, Lecture Hall B3 on October 7th, starting at 3:00 PM.
We look forward to welcoming you to the event.
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